June 23, 2026 / 2 min read
Macrophages May Help Protect and Regenerate Beta Cells
Researchers discover that certain types of macrophages can enhance beta cell survival, function, and proliferation in both mice and humans.
PubMed indexed literature
Library / Cure & Advancements
Cure & Advancements
Where the science of curing Type 1 diabetes actually stands: islet and stem-cell therapies, beta-cell regeneration, immunotherapies, and disease-modifying trials, in plain language.
June 19, 2026 / 2 min read
Macrophages Help Mature Stem Cell-Derived Beta Cells
Researchers discover that adding a specific type of macrophage during stem cell differentiation accelerates the maturation process of beta cells, leading to improved insulin production and blood sugar control.
PubMed indexed literature
June 17, 2026 / 2 min read
What Drives the Destruction of Pancreatic Beta Cells in Type 1 Diabetes?
New research sheds light on how immune cells target and destroy pancreatic beta cells in people with type 1 diabetes.
PubMed indexed literature
June 16, 2026 / 2 min read
Engineering Immune Resilience in Islet Transplantation: A Step Closer to Durable Graft Function
A new review highlights recent advances in pharmacological and cell-intrinsic interventions that can modulate the instant blood-mediated inflammatory reaction (IBMIR) in islet transplantation, a major hurdle in restoring natural insulin control in Type 1 diabetes.
PubMed indexed literature
June 15, 2026 / 2 min read
Stem Cell-Derived Islet Grafts Show Promise for Type 1 Diabetes
Researchers explore the potential of stem cell-derived islets in treating type 1 diabetes, with promising results in animal models.
PubMed indexed literature
June 15, 2026 / 2 min read
Engineering a Cure for Type 1 Diabetes: A Review of Pancreatic Tissue Engineering
Researchers explore the potential of pancreatic tissue engineering to restore insulin production in people with Type 1 diabetes, but challenges remain.
PubMed indexed literature
June 12, 2026 / 2 min read
New Method Generates Pancreatic Islet Organoids from Stem Cells
Scientists have developed a way to create pancreatic islet organoid-like structures from bone marrow stem cells, which could aid in diabetes research and potentially help address the shortage of donor islets for transplantation.
PubMed indexed literature
June 11, 2026 / 2 min read
New Scaffold Design Boosts Success of Islet Transplantation in Mice
Researchers develop nanofibrous scaffolds that enhance vascularization and support long-term islet graft survival in mice, a promising step towards improving islet transplantation for type 1 diabetes.
PubMed indexed literature
June 11, 2026 / 2 min read
New Research Sheds Light on Autoimmune Process in Type 1 Diabetes
Scientists have made a significant discovery about the role of NAMPT activity in driving autoimmune processes that lead to beta-cell death and type 1 diabetes development.
PubMed indexed literature
June 10, 2026 / 2 min read
Young Adults with Type 1 Diabetes Face Considerable Treatment Burden and Lower Quality of Life
A recent study reveals that young adults with type 1 diabetes experience significant treatment burden and moderate quality of life, highlighting the need for improved diabetes care.
PubMed indexed literature
June 8, 2026 / 2 min read
Boosting Islet Transplant Success with Adenosine
Researchers explore the potential of adenosine to improve islet transplantation outcomes by reducing metabolic demand and enhancing hypoxia tolerance.
PubMed indexed literature
June 4, 2026 / 2 min read
Unlocking the Power of MSCs: How Extracellular Vesicles Improve Islet Transplant Success
Researchers have discovered that extracellular vesicles from mesenchymal stromal cells can improve the survival and function of transplanted islets, offering a promising new approach to treating type 1 diabetes.
PubMed indexed literature
May 27, 2026 / 2 min read
Unlocking Early Warning Signs: New Research on Predictive Biomarkers for Type 1 Diabetes
A recent study has made significant progress in identifying potential biomarkers for developing type 1 diabetes, using extracellular vesicle proteomics analysis.
PubMed indexed literature
May 26, 2026 / 2 min read
Unlocking New Insights into Cystic Fibrosis Related Diabetes
Researchers explore emerging topics to improve understanding and management of CFRD, a distinct form of diabetes affecting people with cystic fibrosis.
PubMed indexed literature
May 25, 2026 / 2 min read
New Tool Helps Monitor Islet Transplant Success
A synthetic immunological niche (IN) can detect immune responses and predict transplant outcomes in type 1 diabetes patients.
PubMed indexed literature
May 25, 2026 / 2 min read
Combining GLP1-E2 and Anti-CD3 Therapy Delays Type 1 Diabetes
New research in mice shows that combining a therapy targeting beta cells with an anti-inflammatory treatment can significantly delay the onset of autoimmune diabetes.
PubMed indexed literature
May 19, 2026 / 2 min read
Stem Cell-Derived Islets vs. Primary Islets: How They React to Low Oxygen
A new study reveals that stem cell-derived islets and primary human islets respond differently to low oxygen levels, which could impact the success of cell replacement therapies for Type 1 diabetes.
PubMed indexed literature
May 16, 2026 / 2 min read
Stem Cell-Based Therapies for Type 1 Diabetes: Progress and Challenges
Researchers are making progress in using stem cells to treat type 1 diabetes, but significant challenges remain before this approach can be widely adopted.
PubMed indexed literature
May 14, 2026 / 2 min read
Pancreatic Ductal Cells May Play a Role in Autoimmune Destruction of Beta Cells
New research suggests that pancreatic ductal cells may contribute to the autoimmune destruction of beta cells in Type 1 diabetes, but more studies are needed to understand their role.
PubMed indexed literature
May 8, 2026 / 2 min read
Breakthrough in Xenotransplantation: A Safe and Promising Treatment for Type 1 Diabetes
A recent clinical trial has shown that xenotransplanting porcine islet cells into patients with Type 1 diabetes is safe and effective, offering new hope for those living with the condition.
PubMed indexed literature
May 8, 2026 / 2 min read
Unlocking Beta Cell Health: A New Approach to Type 1 Diabetes
Researchers are exploring the potential of extracellular vesicles to improve our understanding and treatment of type 1 diabetes.
PubMed indexed literature
May 4, 2026 / 2 min read
Engineered Implants Show Promise for Insulin Delivery in Type 1 Diabetes
Researchers develop implantable vascularized endocrine constructs that could provide a new approach to insulin delivery in type 1 diabetes.
PubMed indexed literature
April 30, 2026 / 2 min read
Uncovering the Role of Mitochondria in Type 1 Diabetes Research
Scientists explore how mitochondria contribute to the development of insulin-producing cells from stem cells, a potential alternative solution for type 1 diabetes.
PubMed indexed literature
April 8, 2026 / 2 min read
New Therapies Offer Hope for Type 1 Diabetes
Recent breakthroughs in immunotherapy and gene editing aim to delay or reverse disease progression, but challenges persist.
PubMed indexed literature
April 1, 2026 / 2 min read
Understanding the Root Cause of Type 1 Diabetes: A Shift in Focus
Recent research suggests that pancreatic beta cell defects may play a more significant role in type 1 diabetes development than previously thought, challenging our understanding of the disease.
PubMed indexed literature
March 31, 2026 / 2 min read
Targeted Immunotherapy Shows Promise in Protecting Pancreatic Islet Grafts
Researchers have made a breakthrough in understanding how to protect pancreatic islet grafts from autoimmune destruction, potentially paving the way for new treatments for Type 1 diabetes.
PubMed indexed literature
March 12, 2026 / 2 min read
New Hydrogel Shows Promise in Enhancing Islet Survival and Glycemic Control
Researchers develop an injectable hydrogel that co-delivers oxygen and a growth factor to improve islet transplantation outcomes in diabetic mice.
PubMed indexed literature
January 28, 2026 / 2 min read
New Nanocoating Shows Promise for Islet Survival in Type 1 Diabetes
Researchers have developed a novel nanocoating that may improve the survival of transplanted islets and restore blood sugar control in people with type 1 diabetes.
PubMed indexed literature
January 8, 2026 / 2 min read
Ensuring the Safety and Effectiveness of Pancreatic Beta Cells Derived from Stem Cells
Researchers propose a comprehensive quality control strategy to differentiate induced pluripotent stem cells into pancreatic beta cells for potential use in treating Type 1 diabetes.
PubMed indexed literature
January 8, 2026 / 2 min read
New Method for Locating Transplanted Islets in Type 1 Diabetes Patients
Researchers develop a way to accurately detect transplanted islets in the subcutaneous space using dithizone staining, a potential game-changer for type 1 diabetes treatment.
PubMed indexed literature
January 8, 2026 / 2 min read
Berberine's Effects on Type 1 Diabetes in Rats: A Promising Lead
Researchers investigate the potential of berberine from Berberis vulgaris to regenerate pancreatic beta-cells and improve metabolic function in type 1 diabetic rats.
PubMed indexed literature