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Video still from YouTube community video: Getting Started With Omnipod 5: How the System Works
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Living with T1D/June 26, 2026/3 min read

Getting Started With Omnipod 5: How the System Works

Omnipod 5 is an automated insulin delivery system that works with your Dexcom G6 continuous glucose monitor to help manage blood sugar. Here's what you need to know about how it works and what to expect.

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Key takeaways

  • Omnipod 5 has three main parts: a smartphone app (or controller), small wearable pods, and a Dexcom G6 CGM sensor
  • The system automates insulin delivery by reading glucose values from your Dexcom G6 and adjusting insulin throughout the day
  • Pods are waterproof, tube-free, hold up to 200 units of insulin, and last up to 72 hours before needing replacement
  • You control the system and monitor your data through the Omnipod 5 app on your phone or dedicated controller
  • The two devices must be in direct line of sight for best communication, and Omnipod 5 only works with Dexcom G6

The Three Parts of Your System

Omnipod 5 combines three connected devices that work together to deliver insulin automatically. The first is the Omnipod 5 app, which you'll use on either a compatible smartphone or on a provided controller. This app is your command center—it's where you set up your initial insulin settings, view your glucose data, receive alerts, and send insulin delivery commands.

The second part is the Omnipod 5 pod itself. This is the small, wearable device that actually holds and delivers your insulin. Each pod can hold up to 200 units and lasts up to 72 hours before you'll need to change it. The pods are waterproof and tube-free, so you can wear them discreetly on multiple body sites.

The third essential part is the Dexcom G6 continuous glucose monitor (CGM). This sensor sends your glucose readings to the system, which uses that information to automatically adjust your insulin delivery. Omnipod 5 currently only works with the Dexcom G6, so having an active Dexcom G6 system is necessary to use Omnipod 5 in automated mode.

How Automation Works

The key to Omnipod 5's automation is something called SmartAdjust technology built into the pods. Once your system is set up and running, the pod receives glucose values from your Dexcom G6 sensor and uses that real-time information to adjust your insulin delivery automatically throughout the day. You don't have to manually calculate doses for every meal or correction—the system does this work for you based on the glucose trends it sees.

To get started with automation, you'll enter your prescribed initial insulin settings into the Omnipod 5 app. From there, the app communicates with your pod to activate automated mode, and the pod communicates with your Dexcom G6 to stay informed about your glucose levels.

Setting Up Your Devices Together

Before you place your Dexcom G6 sensor, you'll need to connect it to your Omnipod 5 system. To do this, simply enter and save your Dexcom G6 transmitter serial number into the Omnipod 5 app. This pairing allows the two devices to share information.

For the best communication between your pod and CGM, try to place them in direct line of sight with each other. Avoid placing one on one side of your body and the other on the opposite side, as this can interfere with their connection. You can expect to change your pod a few times before you need to change your Dexcom G6 sensor, since pods last 72 hours while sensors last longer.

Learning Your System

Because Omnipod 5 works hand-in-hand with Dexcom G6, it's important to familiarize yourself with both devices. Be sure to review all the training resources and materials that come with your Dexcom G6 to understand how that sensor works. Your healthcare team and the manufacturers provide guidance to help you get comfortable using both systems together and making the most of the automated features.

Evidence label

Source: YouTube community video. Evidence type: Community video — lay discussion, not peer-reviewed research. Type1Cure is an information and intelligence hub, not a medical advice service. This article summarizes published research and does not provide diagnosis, treatment, or personal medical guidance. Always talk to your own care team before changing anything about your Type 1 diabetes management.

Type1Cure is an information and intelligence hub, not a medical advice service. This article summarizes published research and does not provide diagnosis, treatment, or personal medical guidance. Always talk to your own care team before changing anything about your Type 1 diabetes management.

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