Zimislecel (VX-880)
This is one of the most advanced cell-replacement programs and has reported trial participants reducing or eliminating injected insulin. It still depends on lifelong immunosuppression, which is the trade-off researchers are now trying to remove.
How it works
Fully differentiated, insulin-producing islet cells made from stem cells are infused into the liver's portal vein. Because the cells are donor-derived, recipients take immune-suppressing medicine to protect them.
Live trial status
A Safety, Tolerability, and Efficacy Study of VX-880 in Participants With Type 1 Diabetes
These are research programs pursuing a functional cure or disease modification for type 1 diabetes. None is a confirmed, broadly available cure. Trial status is informational, not medical advice, and not a recruiting offer. Verify eligibility and details with the official trial record and a clinician.
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