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    "T1": "Peer-reviewed literature index",
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    "T3": "Company or press source",
    "T4": "News or broad media source",
    "T5": "Community, creator, podcast, or anecdotal source",
    "T5-preprint": "Preprint, not peer reviewed"
  },
  "medicalDisclaimer": "Type1Cure is an information and research-monitoring product, not medical advice. Verify source details with clinicians and official records before making care decisions.",
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      "detail": "Fetched recruiting Type 1 diabetes studies."
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      "checkedAt": "2026-06-19T08:17:09.379Z",
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  "items": [
    {
      "id": "clinicaltrials:NCT07655076",
      "sourceId": "clinicaltrials_gov_v2",
      "sourceName": "ClinicalTrials.gov",
      "category": "Trials",
      "trustTier": "T0",
      "evidenceLabel": "Official recruiting registry",
      "urgency": "Act",
      "title": "Simultaneous Measurement and Responsive Treatment - Part 2",
      "summary": "RECRUITING, EARLY_PHASE1. Interventions: DPP System (Insulin Pump and Continuous Glucose Monitoring Platform). Locations: Toronto, Ontario, Canada. This research study is testing an investigational dual-port insulin patch pump that integrates a continuous glucose monitor (CGM) in adults with type 1 diabetes. The goal of the study is to better understand how insulin delivery near a CGM sensor affects glucose readings and to collect data to support developm...",
      "whyItMatters": "Recruiting status can change quickly. Families should review official eligibility, location, burden, and care-team fit before sharing health information.",
      "url": "https://clinicaltrials.gov/study/NCT07655076",
      "publishedAt": "2026-06-17",
      "fetchedAt": "2026-06-19T08:17:04.154Z",
      "tags": [
        "trial",
        "recruiting",
        "clinicaltrials.gov"
      ],
      "metadata": {
        "nctId": "NCT07655076",
        "status": "RECRUITING",
        "phase": "EARLY_PHASE1",
        "interventions": "DPP System (Insulin Pump and Continuous Glucose Monitoring Platform)",
        "locations": "Toronto, Ontario, Canada"
      }
    },
    {
      "id": "clinicaltrials:NCT07634770",
      "sourceId": "clinicaltrials_gov_v2",
      "sourceName": "ClinicalTrials.gov",
      "category": "Trials",
      "trustTier": "T0",
      "evidenceLabel": "Official recruiting registry",
      "urgency": "Act",
      "title": "Bioavailability, Biopotency and Food Effect Study of SCD0503 Compared to Subcutaneous Regular Human Insulin",
      "summary": "RECRUITING, PHASE1. Interventions: oral insulin, Placebo A, subcutaneous insulin. Locations: Neuss, North Rhine-Westphalia, Germany. Reason for the study The participants have been diagnosed with type 1 diabetes and are being treated with standard insulin therapy. The sponsor of the study is developing a new insulin-based medicine that can be taken by mouth (orally). For this reason, the investigational product named SCD0503 is to be tested in the study....",
      "whyItMatters": "Recruiting status can change quickly. Families should review official eligibility, location, burden, and care-team fit before sharing health information.",
      "url": "https://clinicaltrials.gov/study/NCT07634770",
      "publishedAt": "2026-06-09",
      "fetchedAt": "2026-06-19T08:17:04.154Z",
      "tags": [
        "trial",
        "recruiting",
        "clinicaltrials.gov"
      ],
      "metadata": {
        "nctId": "NCT07634770",
        "status": "RECRUITING",
        "phase": "PHASE1",
        "interventions": "oral insulin, Placebo A, subcutaneous insulin",
        "locations": "Neuss, North Rhine-Westphalia, Germany"
      }
    },
    {
      "id": "clinicaltrials:NCT07187531",
      "sourceId": "clinicaltrials_gov_v2",
      "sourceName": "ClinicalTrials.gov",
      "category": "Trials",
      "trustTier": "T0",
      "evidenceLabel": "Official recruiting registry",
      "urgency": "Act",
      "title": "SAFety and Efficacy of Human Anti-thymocyte ImmunoGlobUlin SAB-142 ARresting Progression of Type 1 Diabetes",
      "summary": "RECRUITING, PHASE2. Interventions: High Dose SAB-142, Low Dose SAB-142, Placebo. Locations: San Francisco, California, United States | San Jose, California, United States | Aurora, Colorado, United States. This is a Phase 2b, investigator- and participant-blinded, placebo-controlled, parallel-arm study to evaluate the efficacy, safety and tolerability of SAB 142 in patients with Stage 3 New Onset of Type 1 Diabetes (NOT1D).",
      "whyItMatters": "Recruiting status can change quickly. Families should review official eligibility, location, burden, and care-team fit before sharing health information.",
      "url": "https://clinicaltrials.gov/study/NCT07187531",
      "publishedAt": "2026-05-29",
      "fetchedAt": "2026-06-19T08:17:04.154Z",
      "tags": [
        "trial",
        "recruiting",
        "clinicaltrials.gov"
      ],
      "metadata": {
        "nctId": "NCT07187531",
        "status": "RECRUITING",
        "phase": "PHASE2",
        "interventions": "High Dose SAB-142, Low Dose SAB-142, Placebo",
        "locations": "San Francisco, California, United States | San Jose, California, United States | Aurora, Colorado, United States"
      }
    },
    {
      "id": "openfda-device-recall:219288",
      "sourceId": "openfda_device_recalls",
      "sourceName": "openFDA device recalls",
      "category": "Safety",
      "trustTier": "T0",
      "evidenceLabel": "FDA recall database",
      "urgency": "Act",
      "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 CGM iOS App Model/Catalog Number: SW12300 Software Version: Versions 2.9.0 through 2.11.2 Produc...",
      "summary": "A software defect in which a low-priority file I/O check blocks the higher-priority thread responsible for processing estimated glucose values (EGVs) and trend arrows. When the app is running in the background, EGV notifications may queue up and then \"replay\" sequentially when the user brings the app to the foreground, causing the Glucose Compass to flicker through previous EG... Action: On 04/14/2026, the firm sent via the iOS App an \"URGENT: MEDICAL DEVICE CORRECTION NOTIFICATION\" communication informing custome...",
      "whyItMatters": "Device and supply recalls can affect insulin delivery, glucose readings, replacement needs, and urgent family safety decisions.",
      "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219288",
      "publishedAt": "2026-05-11",
      "fetchedAt": "2026-06-19T08:17:04.154Z",
      "tags": [
        "safety",
        "recall",
        "fda",
        "device"
      ],
      "metadata": {
        "cfresId": "219288",
        "recallNumber": "Z-2163-2026",
        "status": "Open, Classified",
        "firm": "Dexcom, Inc.",
        "initiatedAt": "2026-04-14",
        "postedAt": "2026-05-11"
      }
    },
    {
      "id": "openfda-device-recall:219289",
      "sourceId": "openfda_device_recalls",
      "sourceName": "openFDA device recalls",
      "category": "Safety",
      "trustTier": "T0",
      "evidenceLabel": "FDA recall database",
      "urgency": "Act",
      "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 CGM watchOS App Model/Catalog Number: SW13355 Software Version: Versions 2.9.0 through 2.11.2 Pr...",
      "summary": "A software defect in which a low-priority file I/O check blocks the higher-priority thread responsible for processing estimated glucose values (EGVs) and trend arrows. When the app is running in the background, EGV notifications may queue up and then \"replay\" sequentially when the user brings the app to the foreground, causing the Glucose Compass to flicker through previous EG... Action: On 04/14/2026, the firm sent via the iOS App an \"URGENT: MEDICAL DEVICE CORRECTION NOTIFICATION\" communication informing custome...",
      "whyItMatters": "Device and supply recalls can affect insulin delivery, glucose readings, replacement needs, and urgent family safety decisions.",
      "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219289",
      "publishedAt": "2026-05-11",
      "fetchedAt": "2026-06-19T08:17:04.154Z",
      "tags": [
        "safety",
        "recall",
        "fda",
        "device"
      ],
      "metadata": {
        "cfresId": "219289",
        "recallNumber": "Z-2164-2026",
        "status": "Open, Classified",
        "firm": "Dexcom, Inc.",
        "initiatedAt": "2026-04-14",
        "postedAt": "2026-05-11"
      }
    },
    {
      "id": "openfda-device-recall:219290",
      "sourceId": "openfda_device_recalls",
      "sourceName": "openFDA device recalls",
      "category": "Safety",
      "trustTier": "T0",
      "evidenceLabel": "FDA recall database",
      "urgency": "Act",
      "title": "Dexcom, Inc.: Brand Name: Dexcom ONE+ Continuous Glucose Monitoring System Product Name: Dexcom ONE+ iOS CGM App Model/Catalog Number: SW14244 Software Version: versions 1.5.0 and 1.6.0 Product...",
      "summary": "A software defect in which a low-priority file I/O check blocks the higher-priority thread responsible for processing estimated glucose values (EGVs) and trend arrows. When the app is running in the background, EGV notifications may queue up and then \"replay\" sequentially when the user brings the app to the foreground, causing the Glucose Compass to flicker through previous EG... Action: On 04/14/2026, the firm sent via the iOS App an \"URGENT: MEDICAL DEVICE CORRECTION NOTIFICATION\" communication informing custome...",
      "whyItMatters": "Device and supply recalls can affect insulin delivery, glucose readings, replacement needs, and urgent family safety decisions.",
      "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219290",
      "publishedAt": "2026-05-11",
      "fetchedAt": "2026-06-19T08:17:04.154Z",
      "tags": [
        "safety",
        "recall",
        "fda",
        "device"
      ],
      "metadata": {
        "cfresId": "219290",
        "recallNumber": "Z-2165-2026",
        "status": "Open, Classified",
        "firm": "Dexcom, Inc.",
        "initiatedAt": "2026-04-14",
        "postedAt": "2026-05-11"
      }
    },
    {
      "id": "openfda-device-recall:219498",
      "sourceId": "openfda_device_recalls",
      "sourceName": "openFDA device recalls",
      "category": "Safety",
      "trustTier": "T0",
      "evidenceLabel": "FDA recall database",
      "urgency": "Act",
      "title": "North American Rescue LLC.: AIDBAGs are first aid kits of convenience composed of individually labeled devices designed as specialty first aid kits designed for the appropriate level provider to evaluate and...",
      "summary": "Kits contain the McKesson TRUE Metrix PRO Professional Monitoring Blood Glucose System that has been recalled for an issue with the software design of the E-5 Error Code where the meter displays an E-5 error code for a very high blood glucose event (> 600 mg/dL) or when there is a test strip error, which can lead to operator confusion when evaluating patients and a delay in ap... Action: On 3/27/2026, correction notices were emailed to customers asking them to take the following actions: For Health Care Profession...",
      "whyItMatters": "Device and supply recalls can affect insulin delivery, glucose readings, replacement needs, and urgent family safety decisions.",
      "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219498",
      "publishedAt": "2026-04-29",
      "fetchedAt": "2026-06-19T08:17:04.154Z",
      "tags": [
        "safety",
        "recall",
        "fda",
        "device"
      ],
      "metadata": {
        "cfresId": "219498",
        "recallNumber": "Z-1947-2026",
        "status": "Open, Classified",
        "firm": "North American Rescue LLC.",
        "initiatedAt": "2026-03-27",
        "postedAt": "2026-04-29"
      }
    },
    {
      "id": "openfda-device-recall:219130",
      "sourceId": "openfda_device_recalls",
      "sourceName": "openFDA device recalls",
      "category": "Safety",
      "trustTier": "T0",
      "evidenceLabel": "FDA recall database",
      "urgency": "Act",
      "title": "FDA device recall: Omnipod 5 Pods. Model/Catalog number: PT-001662 ASM 5PK Pod STRL OPS G6G7",
      "summary": "Due to a manufacturing defect, certain Omnipod 5 Pods from 49 lots have an internal soft cannula tear that results in insulin leaking into the Pod instead of being delivered to the user regardless of basal or bolus delivery. This defect results from damage to the unexposed portion of the soft cannula during manufacturing, which would result in a compromised fluid path. The pri... Action: Insulet notified consignees via press release and letters sent via email primarily and also text message on 03/12/2026. The pres...",
      "whyItMatters": "Device and supply recalls can affect insulin delivery, glucose readings, replacement needs, and urgent family safety decisions.",
      "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219130",
      "publishedAt": "2026-04-10",
      "fetchedAt": "2026-06-19T08:17:04.154Z",
      "tags": [
        "safety",
        "recall",
        "fda",
        "device"
      ],
      "metadata": {
        "cfresId": "219130",
        "recallNumber": "Z-1797-2026",
        "status": "Open, Classified",
        "initiatedAt": "2026-03-12",
        "postedAt": "2026-04-10"
      }
    },
    {
      "id": "openfda-device-recall:217834",
      "sourceId": "openfda_device_recalls",
      "sourceName": "openFDA device recalls",
      "category": "Safety",
      "trustTier": "T0",
      "evidenceLabel": "FDA recall database",
      "urgency": "Act",
      "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump (MMT-1760, MMT-1761, MMT-1762, MMT-1780, MMT-1781, MMT-1782)",
      "summary": "All Medtronic MiniMed infusion pumps (Paradigm series, 600 series, and BLE 700 series) were found to be affected by unintended over- and under-delivery of insulin when the pump is elevated or lowered relative to the infusion site, respectively, because of changes in gravitational force impacting hydrostatic and hydrodynamic pressures. Insulin over-delivery, which can occur whe... Action: On 2/13/2026, communications began via email, SMS, certified postal mail, and in-app push notifications. Correction notices were...",
      "whyItMatters": "Device and supply recalls can affect insulin delivery, glucose readings, replacement needs, and urgent family safety decisions.",
      "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=217834",
      "publishedAt": "2026-04-02",
      "fetchedAt": "2026-06-19T08:17:04.154Z",
      "tags": [
        "safety",
        "recall",
        "fda",
        "device"
      ],
      "metadata": {
        "cfresId": "217834",
        "recallNumber": "Z-1739-2026",
        "status": "Open, Classified",
        "firm": "Medtronic MiniMed, Inc.",
        "initiatedAt": "2026-02-13",
        "postedAt": "2026-04-02"
      }
    },
    {
      "id": "openfda-device-recall:218909",
      "sourceId": "openfda_device_recalls",
      "sourceName": "openFDA device recalls",
      "category": "Safety",
      "trustTier": "T0",
      "evidenceLabel": "FDA recall database",
      "urgency": "Act",
      "title": "Medtronic MiniMed, Inc.: MiniMed 630G Insulin Pump (MMT-1714, MMT-1715, MMT-1754, MMT-1755)",
      "summary": "All Medtronic MiniMed infusion pumps (Paradigm series, 600 series, and BLE 700 series) were found to be affected by unintended over- and under-delivery of insulin when the pump is elevated or lowered relative to the infusion site, respectively, because of changes in gravitational force impacting hydrostatic and hydrodynamic pressures. Insulin over-delivery, which can occur whe... Action: On 2/13/2026, communications began via email, SMS, certified postal mail, and in-app push notifications. Correction notices were...",
      "whyItMatters": "Device and supply recalls can affect insulin delivery, glucose readings, replacement needs, and urgent family safety decisions.",
      "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=218909",
      "publishedAt": "2026-04-02",
      "fetchedAt": "2026-06-19T08:17:04.154Z",
      "tags": [
        "safety",
        "recall",
        "fda",
        "device"
      ],
      "metadata": {
        "cfresId": "218909",
        "recallNumber": "Z-1740-2026",
        "status": "Open, Classified",
        "firm": "Medtronic MiniMed, Inc.",
        "initiatedAt": "2026-02-13",
        "postedAt": "2026-04-02"
      }
    },
    {
      "id": "openfda-device-recall:218910",
      "sourceId": "openfda_device_recalls",
      "sourceName": "openFDA device recalls",
      "category": "Safety",
      "trustTier": "T0",
      "evidenceLabel": "FDA recall database",
      "urgency": "Act",
      "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump (MMT-1884, MMT-1885, MMT-1886, MMT-1894, MMT-1895, MMT-1896)",
      "summary": "All Medtronic MiniMed infusion pumps (Paradigm series, 600 series, and BLE 700 series) were found to be affected by unintended over- and under-delivery of insulin when the pump is elevated or lowered relative to the infusion site, respectively, because of changes in gravitational force impacting hydrostatic and hydrodynamic pressures. Insulin over-delivery, which can occur whe... Action: On 2/13/2026, communications began via email, SMS, certified postal mail, and in-app push notifications. Correction notices were...",
      "whyItMatters": "Device and supply recalls can affect insulin delivery, glucose readings, replacement needs, and urgent family safety decisions.",
      "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=218910",
      "publishedAt": "2026-04-02",
      "fetchedAt": "2026-06-19T08:17:04.154Z",
      "tags": [
        "safety",
        "recall",
        "fda",
        "device"
      ],
      "metadata": {
        "cfresId": "218910",
        "recallNumber": "Z-1741-2026",
        "status": "Open, Classified",
        "firm": "Medtronic MiniMed, Inc.",
        "initiatedAt": "2026-02-13",
        "postedAt": "2026-04-02"
      }
    },
    {
      "id": "openfda-device-recall:219223",
      "sourceId": "openfda_device_recalls",
      "sourceName": "openFDA device recalls",
      "category": "Safety",
      "trustTier": "T0",
      "evidenceLabel": "FDA recall database",
      "urgency": "Act",
      "title": "Medtronic MiniMed, Inc.: MiniMed 770G Insulin Pump (MMT-1880, MMT-1881, MMT-1882, MMT-1890, MMT-1891, MMT-1892)",
      "summary": "All Medtronic MiniMed infusion pumps (Paradigm series, 600 series, and BLE 700 series) were found to be affected by unintended over- and under-delivery of insulin when the pump is elevated or lowered relative to the infusion site, respectively, because of changes in gravitational force impacting hydrostatic and hydrodynamic pressures. Insulin over-delivery, which can occur whe... Action: On 2/13/2026, communications began via email, SMS, certified postal mail, and in-app push notifications. Correction notices were...",
      "whyItMatters": "Device and supply recalls can affect insulin delivery, glucose readings, replacement needs, and urgent family safety decisions.",
      "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219223",
      "publishedAt": "2026-04-02",
      "fetchedAt": "2026-06-19T08:17:04.154Z",
      "tags": [
        "safety",
        "recall",
        "fda",
        "device"
      ],
      "metadata": {
        "cfresId": "219223",
        "recallNumber": "Z-1742-2026",
        "status": "Open, Classified",
        "firm": "Medtronic MiniMed, Inc.",
        "initiatedAt": "2026-02-13",
        "postedAt": "2026-04-02"
      }
    },
    {
      "id": "openfda-device-recall:219224",
      "sourceId": "openfda_device_recalls",
      "sourceName": "openFDA device recalls",
      "category": "Safety",
      "trustTier": "T0",
      "evidenceLabel": "FDA recall database",
      "urgency": "Act",
      "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump (MMT-1711, MMT-1712, MMT-1751, MMT-1752)",
      "summary": "All Medtronic MiniMed infusion pumps (Paradigm series, 600 series, and BLE 700 series) were found to be affected by unintended over- and under-delivery of insulin when the pump is elevated or lowered relative to the infusion site, respectively, because of changes in gravitational force impacting hydrostatic and hydrodynamic pressures. Insulin over-delivery, which can occur whe... Action: On 2/13/2026, communications began via email, SMS, certified postal mail, and in-app push notifications. Correction notices were...",
      "whyItMatters": "Device and supply recalls can affect insulin delivery, glucose readings, replacement needs, and urgent family safety decisions.",
      "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219224",
      "publishedAt": "2026-04-02",
      "fetchedAt": "2026-06-19T08:17:04.154Z",
      "tags": [
        "safety",
        "recall",
        "fda",
        "device"
      ],
      "metadata": {
        "cfresId": "219224",
        "recallNumber": "Z-1743-2026",
        "status": "Open, Classified",
        "firm": "Medtronic MiniMed, Inc.",
        "initiatedAt": "2026-02-13",
        "postedAt": "2026-04-02"
      }
    },
    {
      "id": "clinicaltrials:NCT05414409",
      "sourceId": "clinicaltrials_gov_v2",
      "sourceName": "ClinicalTrials.gov",
      "category": "Trials",
      "trustTier": "T0",
      "evidenceLabel": "Official recruiting registry",
      "urgency": "Act",
      "title": "The Gut Microbiome in Type 1 Diabetes and Mechanism of Metformin Action",
      "summary": "RECRUITING, PHASE2. Interventions: Metformin. Locations: Indianapolis, Indiana, United States. Ovwerweight and obesity prevalence in persons with T1D has increased, which further complicates management and risk for complications. The proposed study is relevant to public health because it helps us understand the role of the gut microbiome in disease pathophysiology in T1D youth with overweight and obesity as well as potential mechanisms to modify disease.",
      "whyItMatters": "Recruiting status can change quickly. Families should review official eligibility, location, burden, and care-team fit before sharing health information.",
      "url": "https://clinicaltrials.gov/study/NCT05414409",
      "publishedAt": "2025-07-25",
      "fetchedAt": "2026-06-19T08:17:04.154Z",
      "tags": [
        "trial",
        "recruiting",
        "clinicaltrials.gov"
      ],
      "metadata": {
        "nctId": "NCT05414409",
        "status": "RECRUITING",
        "phase": "PHASE2",
        "interventions": "Metformin",
        "locations": "Indianapolis, Indiana, United States"
      }
    },
    {
      "id": "clinicaltrials:NCT06275412",
      "sourceId": "clinicaltrials_gov_v2",
      "sourceName": "ClinicalTrials.gov",
      "category": "Trials",
      "trustTier": "T0",
      "evidenceLabel": "Official recruiting registry",
      "urgency": "Act",
      "title": "Family Intervention for Black Teens With Type 1 Diabetes",
      "summary": "RECRUITING, NA. Interventions: The 3Ms 2.0 Intervention, Educational Attention Control (EAC). Locations: Washington D.C., District of Columbia, United States | Detroit, Michigan, United States | Memphis, Tennessee, United States. The purpose of this study is to conduct a multicenter, randomized effectiveness trial of The 3Ms 2.0 compared to an educational control condition for improving adolescent glycemic control and diabetes-related family relationships...",
      "whyItMatters": "Recruiting status can change quickly. Families should review official eligibility, location, burden, and care-team fit before sharing health information.",
      "url": "https://clinicaltrials.gov/study/NCT06275412",
      "publishedAt": "2025-07-15",
      "fetchedAt": "2026-06-19T08:17:04.154Z",
      "tags": [
        "trial",
        "recruiting",
        "clinicaltrials.gov"
      ],
      "metadata": {
        "nctId": "NCT06275412",
        "status": "RECRUITING",
        "phase": "NA",
        "interventions": "The 3Ms 2.0 Intervention, Educational Attention Control (EAC)",
        "locations": "Washington D.C., District of Columbia, United States | Detroit, Michigan, United States | Memphis, Tennessee, United States"
      }
    },
    {
      "id": "clinicaltrials:NCT06694558",
      "sourceId": "clinicaltrials_gov_v2",
      "sourceName": "ClinicalTrials.gov",
      "category": "Trials",
      "trustTier": "T0",
      "evidenceLabel": "Official recruiting registry",
      "urgency": "Act",
      "title": "Monocytes in Subjects With Type 1 Diabetes and Chronic Kidney Disease",
      "summary": "RECRUITING. Locations: Cleveland, Ohio, United States. This is a cross-sectional study in patients with Type 1 diabetes (TID) and chronic kidney disease (CKD) to test if time in range (TIR) affects the degree of hyperglycemia required for monocyte activation, podocyte injury, and assess if monocyte activation is attenuated by glucagon-like peptide (GLP-1) agonist treatment ex vivo.",
      "whyItMatters": "Recruiting status can change quickly. Families should review official eligibility, location, burden, and care-team fit before sharing health information.",
      "url": "https://clinicaltrials.gov/study/NCT06694558",
      "publishedAt": "2025-06-11",
      "fetchedAt": "2026-06-19T08:17:04.154Z",
      "tags": [
        "trial",
        "recruiting",
        "clinicaltrials.gov"
      ],
      "metadata": {
        "nctId": "NCT06694558",
        "status": "RECRUITING",
        "phase": "",
        "interventions": "",
        "locations": "Cleveland, Ohio, United States"
      }
    },
    {
      "id": "crossref:10.32598/jccnc.7.1.356.1",
      "sourceId": "crossref_works",
      "sourceName": "Crossref",
      "category": "Research",
      "trustTier": "T1",
      "evidenceLabel": "DOI-indexed publication",
      "urgency": "Track",
      "title": "Comparing of the Effects of Acceptance and Commitment Therapy and Emotion Regulation Training on Diabetes Empowerment",
      "summary": "Journal of Client-Centered Nursing Care. Type: journal-article. Background: Diabetes mellitus is a widely diffused chronic condition that affects several aspects of patients’ lives. The patient’s life in this condition depends on diabetes management ability. Therefore, this study aimed to compare the e...",
      "whyItMatters": "Crossref expands literature discovery beyond PubMed, but each item still needs relevance and evidence review before it becomes a recommendation.",
      "url": "https://doi.org/10.32598/jccnc.7.1.356.1",
      "publishedAt": "2121-02-01",
      "fetchedAt": "2026-06-19T08:17:04.154Z",
      "tags": [
        "research",
        "crossref",
        "doi"
      ],
      "metadata": {
        "doi": "10.32598/jccnc.7.1.356.1",
        "publisher": "Negah Scientific Publisher",
        "container": "Journal of Client-Centered Nursing Care",
        "type": "journal-article"
      }
    },
    {
      "id": "crossref:10.22179/revmacn.20.482",
      "sourceId": "crossref_works",
      "sourceName": "Crossref",
      "category": "Research",
      "trustTier": "T1",
      "evidenceLabel": "DOI-indexed publication",
      "urgency": "Track",
      "title": "Geographical distribution of Corydoras micracanthus Regan 1912 (Siluriformes: Callichthyidae), with comments on its behavior and type locality.",
      "summary": "Revista del Museo Argentino de Ciencias Naturales. Type: journal-article",
      "whyItMatters": "Crossref expands literature discovery beyond PubMed, but each item still needs relevance and evidence review before it becomes a recommendation.",
      "url": "https://doi.org/10.22179/revmacn.20.482",
      "publishedAt": "2108-01-01",
      "fetchedAt": "2026-06-19T08:17:04.154Z",
      "tags": [
        "research",
        "crossref",
        "doi"
      ],
      "metadata": {
        "doi": "10.22179/revmacn.20.482",
        "publisher": "Museo Argentino de Ciencia Naturales",
        "container": "Revista del Museo Argentino de Ciencias Naturales",
        "type": "journal-article"
      }
    },
    {
      "id": "crossref:10.5455/jmhe.2015.08.015",
      "sourceId": "crossref_works",
      "sourceName": "Crossref",
      "category": "Research",
      "trustTier": "T1",
      "evidenceLabel": "DOI-indexed publication",
      "urgency": "Track",
      "title": "Re-Evaluating the Efficacy of the Aqueous Leaf Extract of Bridelia ferrugenia and its Potential Combination with Metformin in the Management of Diabetes Mellitus",
      "summary": "Journal of Medicinal Herbs and Ethnomedicine. Type: journal-article",
      "whyItMatters": "Crossref expands literature discovery beyond PubMed, but each item still needs relevance and evidence review before it becomes a recommendation.",
      "url": "https://doi.org/10.5455/jmhe.2015.08.015",
      "publishedAt": "2105-01-01",
      "fetchedAt": "2026-06-19T08:17:04.154Z",
      "tags": [
        "research",
        "crossref",
        "doi"
      ],
      "metadata": {
        "doi": "10.5455/jmhe.2015.08.015",
        "publisher": "Update Publishing House",
        "container": "Journal of Medicinal Herbs and Ethnomedicine",
        "type": "journal-article"
      }
    },
    {
      "id": "crossref:10.7900/jot.2011may12.1971",
      "sourceId": "crossref_works",
      "sourceName": "Crossref",
      "category": "Research",
      "trustTier": "T1",
      "evidenceLabel": "DOI-indexed publication",
      "urgency": "Track",
      "title": "A Birkhoff type transitivity theorem for non-separable completely metrizable spaces with applications to linear dynamics",
      "summary": "Journal of Operator Theory. Type: journal-article",
      "whyItMatters": "Crossref expands literature discovery beyond PubMed, but each item still needs relevance and evidence review before it becomes a recommendation.",
      "url": "https://doi.org/10.7900/jot.2011may12.1971",
      "publishedAt": "2103-07-24",
      "fetchedAt": "2026-06-19T08:17:04.154Z",
      "tags": [
        "research",
        "crossref",
        "doi"
      ],
      "metadata": {
        "doi": "10.7900/jot.2011may12.1971",
        "publisher": "Theta Foundation",
        "container": "Journal of Operator Theory",
        "type": "journal-article"
      }
    },
    {
      "id": "crossref:10.23975/bjvetr.2031.175855",
      "sourceId": "crossref_works",
      "sourceName": "Crossref",
      "category": "Research",
      "trustTier": "T1",
      "evidenceLabel": "DOI-indexed publication",
      "urgency": "Track",
      "title": "HISTOLOGICAL CHARACTERIZATION OF PNEUMOCYTES TYPE I AND PNEUMOCYTE TYPE II: A SUBJECT REVIEW",
      "summary": "Basrah Journal of Veterinary Research. Type: journal-article",
      "whyItMatters": "Crossref expands literature discovery beyond PubMed, but each item still needs relevance and evidence review before it becomes a recommendation.",
      "url": "https://doi.org/10.23975/bjvetr.2031.175855",
      "publishedAt": "2031-08-01",
      "fetchedAt": "2026-06-19T08:17:04.154Z",
      "tags": [
        "research",
        "crossref",
        "doi"
      ],
      "metadata": {
        "doi": "10.23975/bjvetr.2031.175855",
        "publisher": "Basrah Journal of Veterinary Research",
        "container": "Basrah Journal of Veterinary Research",
        "type": "journal-article"
      }
    },
    {
      "id": "crossref:10.3917/spub.pr2.0051",
      "sourceId": "crossref_works",
      "sourceName": "Crossref",
      "category": "Research",
      "trustTier": "T1",
      "evidenceLabel": "DOI-indexed publication",
      "urgency": "Track",
      "title": "Expériences et recommandations à l’intégration du diabète de type 1 par les acteurs du système de santé au Cameroun – Une étude qualitative",
      "summary": "Santé Publique. Type: journal-article. Introduction : L’intégration de la prise en charge du diabète de type 1 (DT1) au Cameroun est un défi. En dépit de certaines initiatives de fourniture d’insuline gratuite aux enfants, la prise en charge est encore insuffisante. But de l’ét...",
      "whyItMatters": "Crossref expands literature discovery beyond PubMed, but each item still needs relevance and evidence review before it becomes a recommendation.",
      "url": "https://doi.org/10.3917/spub.pr2.0051",
      "publishedAt": "2030-01-01",
      "fetchedAt": "2026-06-19T08:17:04.154Z",
      "tags": [
        "research",
        "crossref",
        "doi"
      ],
      "metadata": {
        "doi": "10.3917/spub.pr2.0051",
        "publisher": "CAIRN.INFO",
        "container": "Santé Publique",
        "type": "journal-article"
      }
    },
    {
      "id": "crossref:10.21608/ejmm.2026.490039.2433",
      "sourceId": "crossref_works",
      "sourceName": "Crossref",
      "category": "Research",
      "trustTier": "T1",
      "evidenceLabel": "DOI-indexed publication",
      "urgency": "Track",
      "title": "Association of Two Genetic Variants (rs3765467 and rs1050450) Polymorphisms with Type 2 Diabetes Mellitus in Iraqi Patients Undergoing Hemodialysis",
      "summary": "Egyptian Journal of Medical Microbiology. Type: journal-article",
      "whyItMatters": "Crossref expands literature discovery beyond PubMed, but each item still needs relevance and evidence review before it becomes a recommendation.",
      "url": "https://doi.org/10.21608/ejmm.2026.490039.2433",
      "publishedAt": "2027-07-01",
      "fetchedAt": "2026-06-19T08:17:04.154Z",
      "tags": [
        "research",
        "crossref",
        "doi"
      ],
      "metadata": {
        "doi": "10.21608/ejmm.2026.490039.2433",
        "publisher": "Egyptian Knowledge Bank",
        "container": "Egyptian Journal of Medical Microbiology",
        "type": "journal-article"
      }
    },
    {
      "id": "crossref:10.22158/eltls.v8n3p21",
      "sourceId": "crossref_works",
      "sourceName": "Crossref",
      "category": "Research",
      "trustTier": "T1",
      "evidenceLabel": "DOI-indexed publication",
      "urgency": "Track",
      "title": "A Multimodal Discourse Analysis of Interpersonal Meaning in New-Type Farmers' Agricultural Promotion Short Videos on Douyin",
      "summary": "English Language Teaching and Linguistics Studies. Type: journal-article. This study selects 15 short videos published over the past year by new-type farmers (xin nong ren) on Douyin as research corpus. It adopts systemic functional grammar’s interpersonal meaning theory, visual grammar’s interactive meaning the...",
      "whyItMatters": "Crossref expands literature discovery beyond PubMed, but each item still needs relevance and evidence review before it becomes a recommendation.",
      "url": "https://doi.org/10.22158/eltls.v8n3p21",
      "publishedAt": "2027-05-07",
      "fetchedAt": "2026-06-19T08:17:04.154Z",
      "tags": [
        "research",
        "crossref",
        "doi"
      ],
      "metadata": {
        "doi": "10.22158/eltls.v8n3p21",
        "publisher": "Scholink Co, Ltd.",
        "container": "English Language Teaching and Linguistics Studies",
        "type": "journal-article"
      }
    },
    {
      "id": "pubmed:42070103",
      "sourceId": "pubmed_ncbi_eutilities",
      "sourceName": "PubMed",
      "category": "Research",
      "trustTier": "T1",
      "evidenceLabel": "PubMed indexed literature",
      "urgency": "Track",
      "title": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation.",
      "summary": "Islets. Authors: Monajemi M, Craciun AS, Huang Q. Journal Article",
      "whyItMatters": "This belongs in the research watch lane for clinical relevance review, evidence labeling, and parent-readable interpretation before any action is implied.",
      "url": "https://pubmed.ncbi.nlm.nih.gov/42070103/",
      "publishedAt": "2026-12-31",
      "fetchedAt": "2026-06-19T08:17:04.154Z",
      "tags": [
        "research",
        "pubmed",
        "type 1 diabetes"
      ],
      "metadata": {
        "pmid": "42070103",
        "journal": "Islets",
        "publicationTypes": [
          "Journal Article"
        ]
      }
    },
    {
      "id": "pubmed:42017902",
      "sourceId": "pubmed_ncbi_eutilities",
      "sourceName": "PubMed",
      "category": "Research",
      "trustTier": "T1",
      "evidenceLabel": "PubMed indexed literature",
      "urgency": "Track",
      "title": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review.",
      "summary": "Islets. Authors: De Taeye S, Bottino R, Cooper DKC. Journal Article, Review, Historical Article",
      "whyItMatters": "This belongs in the research watch lane for clinical relevance review, evidence labeling, and parent-readable interpretation before any action is implied.",
      "url": "https://pubmed.ncbi.nlm.nih.gov/42017902/",
      "publishedAt": "2026-12-31",
      "fetchedAt": "2026-06-19T08:17:04.154Z",
      "tags": [
        "research",
        "pubmed",
        "type 1 diabetes"
      ],
      "metadata": {
        "pmid": "42017902",
        "journal": "Islets",
        "publicationTypes": [
          "Journal Article",
          "Review",
          "Historical Article"
        ]
      }
    },
    {
      "id": "pubmed:41774510",
      "sourceId": "pubmed_ncbi_eutilities",
      "sourceName": "PubMed",
      "category": "Research",
      "trustTier": "T1",
      "evidenceLabel": "PubMed indexed literature",
      "urgency": "Track",
      "title": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats.",
      "summary": "Organogenesis. Authors: Shan J, Wang H, Zhu G. Journal Article",
      "whyItMatters": "This belongs in the research watch lane for clinical relevance review, evidence labeling, and parent-readable interpretation before any action is implied.",
      "url": "https://pubmed.ncbi.nlm.nih.gov/41774510/",
      "publishedAt": "2026-12-31",
      "fetchedAt": "2026-06-19T08:17:04.154Z",
      "tags": [
        "research",
        "pubmed",
        "type 1 diabetes"
      ],
      "metadata": {
        "pmid": "41774510",
        "journal": "Organogenesis",
        "publicationTypes": [
          "Journal Article"
        ]
      }
    },
    {
      "id": "pubmed:41823267",
      "sourceId": "pubmed_ncbi_eutilities",
      "sourceName": "PubMed",
      "category": "Research",
      "trustTier": "T1",
      "evidenceLabel": "PubMed indexed literature",
      "urgency": "Track",
      "title": "Role of small intronic RNAs in the crosstalk between immune cells and β-cells during type 1 diabetes development.",
      "summary": "RNA biology. Authors: Poddar S, Brozzi F, Cosentino C. Journal Article, Research Support, Non-U.S. Gov't",
      "whyItMatters": "This belongs in the research watch lane for clinical relevance review, evidence labeling, and parent-readable interpretation before any action is implied.",
      "url": "https://pubmed.ncbi.nlm.nih.gov/41823267/",
      "publishedAt": "2026-12-01",
      "fetchedAt": "2026-06-19T08:17:04.154Z",
      "tags": [
        "research",
        "pubmed",
        "type 1 diabetes"
      ],
      "metadata": {
        "pmid": "41823267",
        "journal": "RNA biology",
        "publicationTypes": [
          "Journal Article",
          "Research Support, Non-U.S. Gov't"
        ]
      }
    },
    {
      "id": "pubmed:42306051",
      "sourceId": "pubmed_ncbi_eutilities",
      "sourceName": "PubMed",
      "category": "Research",
      "trustTier": "T1",
      "evidenceLabel": "PubMed indexed literature",
      "urgency": "Track",
      "title": "Co-transplantation of pancreatic islets with adipose-derived mesenchymal stem cells in vascularized kidney ECM scaffolds to restore type 1 diabetes mellitus.",
      "summary": "Bioactive materials. Authors: Choi M, Shanto PC, Fahad MAA. Journal Article",
      "whyItMatters": "This belongs in the research watch lane for clinical relevance review, evidence labeling, and parent-readable interpretation before any action is implied.",
      "url": "https://pubmed.ncbi.nlm.nih.gov/42306051/",
      "publishedAt": "2026-11-01",
      "fetchedAt": "2026-06-19T08:17:04.154Z",
      "tags": [
        "research",
        "pubmed",
        "type 1 diabetes"
      ],
      "metadata": {
        "pmid": "42306051",
        "journal": "Bioactive materials",
        "publicationTypes": [
          "Journal Article"
        ]
      }
    },
    {
      "id": "pubmed:41543436",
      "sourceId": "pubmed_ncbi_eutilities",
      "sourceName": "PubMed",
      "category": "Research",
      "trustTier": "T1",
      "evidenceLabel": "PubMed indexed literature",
      "urgency": "Track",
      "title": "Metabolic Programming of β-Cell Fate, State, and Function through Time and Space.",
      "summary": "Physiology (Bethesda, Md.). Authors: MacDonald TL, Bonner-Weir S. Journal Article, Review, Research Support, Non-U.S. Gov't",
      "whyItMatters": "This belongs in the research watch lane for clinical relevance review, evidence labeling, and parent-readable interpretation before any action is implied.",
      "url": "https://pubmed.ncbi.nlm.nih.gov/41543436/",
      "publishedAt": "2026-09-01",
      "fetchedAt": "2026-06-19T08:17:04.154Z",
      "tags": [
        "research",
        "pubmed",
        "type 1 diabetes"
      ],
      "metadata": {
        "pmid": "41543436",
        "journal": "Physiology (Bethesda, Md.)",
        "publicationTypes": [
          "Journal Article",
          "Review",
          "Research Support, Non-U.S. Gov't"
        ]
      }
    },
    {
      "id": "pubmed:42143506",
      "sourceId": "pubmed_ncbi_eutilities",
      "sourceName": "PubMed",
      "category": "Research",
      "trustTier": "T1",
      "evidenceLabel": "PubMed indexed literature",
      "urgency": "Track",
      "title": "The evolution of CAR therapies across oncology and autoimmunity: mechanistic insights and therapeutic innovations.",
      "summary": "International immunopharmacology. Authors: Abd El-Fattah EE, Hamdy R, Soliman SSM. Journal Article, Review",
      "whyItMatters": "This belongs in the research watch lane for clinical relevance review, evidence labeling, and parent-readable interpretation before any action is implied.",
      "url": "https://pubmed.ncbi.nlm.nih.gov/42143506/",
      "publishedAt": "2026-08-01",
      "fetchedAt": "2026-06-19T08:17:04.154Z",
      "tags": [
        "research",
        "pubmed",
        "type 1 diabetes"
      ],
      "metadata": {
        "pmid": "42143506",
        "journal": "International immunopharmacology",
        "publicationTypes": [
          "Journal Article",
          "Review"
        ]
      }
    },
    {
      "id": "pubmed:41967811",
      "sourceId": "pubmed_ncbi_eutilities",
      "sourceName": "PubMed",
      "category": "Research",
      "trustTier": "T1",
      "evidenceLabel": "PubMed indexed literature",
      "urgency": "Track",
      "title": "Cryopreservation of stem cell-derived aggregates for type 1 diabetes cell therapy: Considerations and challenges.",
      "summary": "Journal of controlled release : official journal of the Controlled Release Society. Authors: Barsukova AD, Weng L, Szymanska-Vandendriessche K. Journal Article, Review, Research Support, Non-U.S. Gov't",
      "whyItMatters": "This belongs in the research watch lane for clinical relevance review, evidence labeling, and parent-readable interpretation before any action is implied.",
      "url": "https://pubmed.ncbi.nlm.nih.gov/41967811/",
      "publishedAt": "2026-07-10",
      "fetchedAt": "2026-06-19T08:17:04.154Z",
      "tags": [
        "research",
        "pubmed",
        "type 1 diabetes"
      ],
      "metadata": {
        "pmid": "41967811",
        "journal": "Journal of controlled release : official journal of the Controlled Release Society",
        "publicationTypes": [
          "Journal Article",
          "Review",
          "Research Support, Non-U.S. Gov't"
        ]
      }
    },
    {
      "id": "pubmed:42302798",
      "sourceId": "pubmed_ncbi_eutilities",
      "sourceName": "PubMed",
      "category": "Research",
      "trustTier": "T1",
      "evidenceLabel": "PubMed indexed literature",
      "urgency": "Track",
      "title": "Early-stage type 1 diabetes: is there a role for lifestyle modifications?",
      "summary": "The lancet. Diabetes & endocrinology. Authors: Papanikolaou T, Andrews RC, Cockcroft E. Journal Article",
      "whyItMatters": "This belongs in the research watch lane for clinical relevance review, evidence labeling, and parent-readable interpretation before any action is implied.",
      "url": "https://pubmed.ncbi.nlm.nih.gov/42302798/",
      "publishedAt": "2026-07-01",
      "fetchedAt": "2026-06-19T08:17:04.154Z",
      "tags": [
        "research",
        "pubmed",
        "type 1 diabetes"
      ],
      "metadata": {
        "pmid": "42302798",
        "journal": "The lancet. Diabetes & endocrinology",
        "publicationTypes": [
          "Journal Article"
        ]
      }
    },
    {
      "id": "pubmed:42273282",
      "sourceId": "pubmed_ncbi_eutilities",
      "sourceName": "PubMed",
      "category": "Research",
      "trustTier": "T1",
      "evidenceLabel": "PubMed indexed literature",
      "urgency": "Track",
      "title": "Triple islet autoantibody-positive type 1 diabetes in Japanese stiff-person syndrome despite a protective HLA haplotype.",
      "summary": "JCEM case reports. Authors: Suenaga M, Ogiso K, Takeuchi N. Case Reports, Journal Article",
      "whyItMatters": "This belongs in the research watch lane for clinical relevance review, evidence labeling, and parent-readable interpretation before any action is implied.",
      "url": "https://pubmed.ncbi.nlm.nih.gov/42273282/",
      "publishedAt": "2026-07-01",
      "fetchedAt": "2026-06-19T08:17:04.154Z",
      "tags": [
        "research",
        "pubmed",
        "type 1 diabetes"
      ],
      "metadata": {
        "pmid": "42273282",
        "journal": "JCEM case reports",
        "publicationTypes": [
          "Case Reports",
          "Journal Article"
        ]
      }
    },
    {
      "id": "pubmed:42272327",
      "sourceId": "pubmed_ncbi_eutilities",
      "sourceName": "PubMed",
      "category": "Research",
      "trustTier": "T1",
      "evidenceLabel": "PubMed indexed literature",
      "urgency": "Track",
      "title": "Sustained Glycaemic Control and Preserved Beta-Cell Function in Newly Diagnosed Type 1 Diabetes Treated With Semaglutide.",
      "summary": "Diabetes/metabolism research and reviews. Authors: Carollo M, Martinenghi S, Gallo A. Letter",
      "whyItMatters": "This belongs in the research watch lane for clinical relevance review, evidence labeling, and parent-readable interpretation before any action is implied.",
      "url": "https://pubmed.ncbi.nlm.nih.gov/42272327/",
      "publishedAt": "2026-07-01",
      "fetchedAt": "2026-06-19T08:17:04.154Z",
      "tags": [
        "research",
        "pubmed",
        "type 1 diabetes"
      ],
      "metadata": {
        "pmid": "42272327",
        "journal": "Diabetes/metabolism research and reviews",
        "publicationTypes": [
          "Letter"
        ]
      }
    },
    {
      "id": "pubmed:42265980",
      "sourceId": "pubmed_ncbi_eutilities",
      "sourceName": "PubMed",
      "category": "Research",
      "trustTier": "T1",
      "evidenceLabel": "PubMed indexed literature",
      "urgency": "Track",
      "title": "A Comparison of the Effects of the Timing of Resistance Exercise on Glucose Levels Within the Target Range in People With Type 1 Diabetes (TREX Study): A Randomized Crossover Trial.",
      "summary": "Diabetes/metabolism research and reviews. Authors: Ozairi ESA, Hamdan YG, Awadhi AAA. Journal Article, Randomized Controlled Trial, Comparative Study",
      "whyItMatters": "This belongs in the research watch lane for clinical relevance review, evidence labeling, and parent-readable interpretation before any action is implied.",
      "url": "https://pubmed.ncbi.nlm.nih.gov/42265980/",
      "publishedAt": "2026-07-01",
      "fetchedAt": "2026-06-19T08:17:04.154Z",
      "tags": [
        "research",
        "pubmed",
        "type 1 diabetes"
      ],
      "metadata": {
        "pmid": "42265980",
        "journal": "Diabetes/metabolism research and reviews",
        "publicationTypes": [
          "Journal Article",
          "Randomized Controlled Trial",
          "Comparative Study"
        ]
      }
    }
  ]
}
